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Main Squeeze Natural Foods Cafe


Main Squeeze has been serving healthy, delicious food, fresh juices and smoothies since 1998.  We are the only vegetarian cafe in mid Missouri and are proud to serve organic and locally sourced foods.


“The food you eat can be either the safest and most powerful form of medicine or the slowest form of poison.” ― Ann Wigmore

At Main Squeeze we serve healthy, wholesome foods with an emphasis on organic and local foods.  Our cafe menu features a variety of salads, wraps, sandwiches and hot dishes.  We cook from scratch and prepare dishes healthfully but with loads of flavor.  Our fresh juices are squeezed to order from organic produce, and our smoothies are 100% fruit and organic juice.  Our commitment is to keep it simple, fresh and delicious.  More than half of our menu is vegan and we have lots of gluten free options as well, including our homemade baked goods.

Main Squeeze is on a mission to promote healthy, plant-based eating, while operating as sustainably as possible.  For almost 2 decades we have composted all of our food waste, creating rich soil for our garden that in turn rewards us with seasonal produce, herbs and flowers for the cafe.  We buy from more than a dozen local farms and more than 80% of our purchases are certified organic.  We love our community and have supported many worthwhile causes over the years including Centro Latino, Planned Parenthood, The Central MO Humane Society, Columbia Second Chance and KOPN Community Radio.  Currently we match customer contributions dollar for dollar to buy garden rows with the Columbia Center for Urban Agriculture which in turn grows food for the hungry in our community.